Words cannot express how much I love the Oatmeal and this post the created that I'm sure ALL us fellow artists, freelancers, designers can relate to!
I think this this is one of the reasons why I shy away from web design, aside from the obvious web compatibility issues. Web design is just one of the most tedious things that always turns into a very long project, unless you have amazing clients (in which I have).
I don't think anyone understands what battles us designers go through and how it is impossible to make "everything pop" and why you gotta trust your artist sometimes.